you can always try a few games with mame, sure but don't expect too much. And just for your information, between the version made for amiga (0.35 or so) and current morphos version (0.120), about 8 years have passed and mame itself became at least 3-4 times slower (while being much more rich and accurate).
I's suggest you use the oldest mame versions you can. I think the oldest one you can find on my pages is 0.60 or so. They're not available anymore, but easily reachable with webarchive. I can reupload them if you really need.