Afterwards copy should be faster. (In fact you can change buffers even during a slow copy to speed it up) Same is done internally when booting from CD-Drive. It makes no sense to increase buffers as each buffer is 2K. It is not done by default as most users do not need the CDROM at all. You can add the line to your user-startup adding >NIL: of course.
Bigger values are of course possible, too, but you may not experience any speedup. Same works for HDD and USB drives.
Unlike the CD/DVD-ROM you can change default values using HDConfig,too. By default they are set to 64. For HDD I recomment 4096.