Possible yes, feasable no.

Writing such a VM would be a gigantic task even if you had the support of the guest OS provider to write drivers to it.

Without it you would need to "emulate" an X5000 inside it so you could use the X5000 version of the guest OS.

Another way might be a port of UAE with "passthrough" PPC-EMU running the Amiga version of the guest OS.

Still wouldn't touch the lack of accces to the 2nd core on the host OS.