jPV : I have two PS4's controllers too but they don't work with Tower 57 (no problem with others games...).

How did you do this trick ?
Did you modify the configuration in Poseidon ? Here and by default, it's a "Wireless controller", binding usbaudio.class and hid.class, and it merges port 1 to USB.
Or maybe the controllers_mos.ini ? A [Wireless controller] configuration is in my .ini file but Tower 57 doesn't recognize my PS4' controller...

It's like Tower 57 doesn't recognize HID controllers. But it recognizes automagically the XBox360's controller which uses xbox360.class...

I bang my head on the wall !

--
/me maybe bought XBox360's controllers for nothing !